COMLEX-USA, the Comprehensive Osteopathic Medical Licensure Examination of the United States, is the series of examinations osteopathic medical students take as a condition of graduation, and for medical licensure purposes. The National Board of Osteopathic Medical Examiners (NBOME) recognizes there are a number of secondary uses for COMLEX-USA scores, including use by Residency Program Directors to help in assessing applicants.